TP53 and breast cancer: In a time and dose‐dependent manner, a chloroform‐based extract of fenugreek seed may significantly decrease the viability of MCF‐7 breast cancer cells by triggering apoptosis related to improved articulation of Fas, Bax, FADD, Bak, and Caspase 3, 8, 9, p53 (Khoja et al. 2011).