SPP1 and infection: The Proteome profiler analysis revealed that throughout the infection, pentraxin, osteopontin, myeloperoxidase, and chitinase 3-like 1 (Chil3L1) levels remained elevated compared to 0 dpi, with an early increase in matrix metalloproteinase-9 (MMP-9) expression observed at 3, and 5 dpi, and a continuous rise in regenerating islet-derived protein 3 gamma (Reg3G).