MYC and neoplasm: Irradiation led to a significant decrease in the c-MYC mRNA level in assembloids subjected to 3 Gy X-rays 7 days post-irradiation and in the co-culture of organoid slices and tumor-like cells exposed to 15 Gy X-rays 20 days post-irradiation when compared to the sham-irradiated controls (Figure 9A).