BAX and coronary artery disorder: Many more genes have been implicated in CAD, with BCL-2 rs17757541 C > G polymorphism showing close correlation with CAD in a Chinese population (76), p53, also an upstream regulator of Bax, accumulating in monocytes of CAD patients against a background of oxidative stress (77) (which has also been indicated by Panther 2016 database).