On the other hand, this mixture of IOLE AgNPs had potent anti-oxidant and anti-inflammatory properties which reduced the oxidative stress status besides suppressing the pro-inflammatory cytokines post-infection, which was responsible for persistent inflammation that mediated lung damage according to Jangid et al. [62] and Parvin et al. [63] who confirmed that the nano-particles modulated chemokines and growth factors like G-CSF and CXCL1 for tissue repair. The gene discussed is CXCL1; the disease is infection.