SLC2A1 and thyroid gland carcinoma: For instance, HIF-1α can increase GLUT1 and GLUT3 expression, increase the uptake of glucose by thyroid cancer cells, and provide substrates for glycolysis to meet their energy needs through SLC2A1 (encoding GLUT1) and SLC2A3 (encoding GLUT3) (Yang et al., 2024).