In gastric cancer cells, PDLIM1 (PDZ and LIM domain protein 1) interacted with HK2 (Hexokinase 2) to drive glycolysis, proliferation, migration, and apoptosis resistance via Wnt/β-catenin signaling, particularly under glucose-deprived conditions (Lei et al., 2024). The gene discussed is HK2; the disease is gastric cancer.