In our study, treatment of cystinotic ciPTECs with the demethylating agent decitabine successfully increased the expression of key transporters, including SLC7A7, AQP1, and CUBN. It is noteworthy that these genes were already transcriptionally active in HD cells, likely making them more responsive to upregulation upon treatment. This evidence concerns the gene SLC7A7 and Huntington disease.