We measured the mRNA expression levels of autophagy-related genes including Beclin-1, LC3-II, ATG5, and ATG7 under various treatment conditions using Idelalisib, MK2206, and Everolimus as PI3K/AKT/mTOR inhibitors in the HL-60 AML cell line (Fig. 4). Here, MTOR is linked to acute myeloid leukemia.