Altogether, compared to ccRCC and tRCC, the significant high-frequency occurrence of 17q gain in CDC was associated with increased ribosome biogenesis and cell migration owing to the cis-acting elements on UTP6 and HN1, respectively (Fig. 4P). This evidence concerns the gene JPT1 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.