A total of 23 genes (GAS6, SERPING1, PLSCR1, CYP1B1, CTNNAL1, ATF3, TNFSF10, ADM, S100A8, C1QB, BPGM, GADD45G, FGF13, MYOM2, JAK2, SOCS3, KCNJ2, CLEC2B, C1QA, CHPT1, KREMEN1, C1QC, CMBL) were identified as Shared cross-talk genes between TB and T2DM based on the intersection of WGCNA modules and DEGs (Figure 1F). Here, JAK2 is linked to type 2 diabetes mellitus.