Multivariate logistic regression analyses were performed to determine the factors associated with late-life depression and chronic pain after adjusting age, sex, body mass index, race, living, working, smoking, drinking, systolic blood pressure, diastolic blood pressure, heart rate, red blood cell, hemoglobin, white blood cell, neutrophil, uric acid, creatinine, urea nitrogen, alanine aminotransferase, aspartate aminotransferase, total protein, and albumin. The gene discussed is ALB; the disease is depressive symptom measurement.