PCa‐specific hypoxia‐related gene sets (Table S4, Supporting Information)[18] demonstrated broad upregulation in PC‐treated cells (Figure 7B), corroborated by HIF‐1α protein induction exceeding levels observed under 0.5% O2 hypoxia or CoCl2 treatment (Figure 7C). Here, HIF1A is linked to posterior cortical atrophy.