By applying SHAP, several key features associated with pCR in BC patients undergoing NAC were identified, then sTILs emerged as the most important predictor, followed by HER2 status, age, lymphatic metastasis, aspect ratio, Ki‐67 expression, tumor size, RDW, menopausal status, posterior echo, PDW, and PR. Here, ERBB2 is linked to neoplasm.