Recent literature has shown that the magnitude of the APOE4 effect differs across Hispanic subgroups (Granot‐Hershkovitz et al. 2023), with some populations (e.g., Mexican Americans) showing weaker or non‐significant associations with AD or related dementias, while others (e.g., Central or South American ancestry) retain a stronger risk effect (Huggins et al. 2023). This evidence concerns the gene APOE and dementia.