M Canöz et al. explored the relationship between inflammatory markers, asthma, and obesity, revealing significantly elevated levels of leptin, C-Reactive Protein (CRP), erythrocyte sedimentation rate, Tumor Necrosis Factor-α (TNF-α), and Interleukin-6 (IL-6) in patients compared to healthy controls (p < 0.01).10 Here, TNF is linked to obesity due to melanocortin 4 receptor deficiency.