Compared to endotype 1, endotype 2 T1D is characterised by a slightly delayed onset, less rapid over time decline in serum c‐peptide levels and body weight, lower autoantibody titres with anti‐glutamic acid decarboxylase autoantibodies being predominant over anti‐insulin antibodies, and higher body weight (usually in the normal range). This evidence concerns the gene INS and type 1 diabetes mellitus.