Briefly, prenatal treatment with BPA results in metabolic disruptions like insulin resistance and adipocyte hypertrophy in sheep (Veiga-Lopez et al., 2016), lower birthweight, adulthood obesity, impaired glucose and insulin homeostasis in mice (Susiarjo et al., 2015), increased plasma triglyceride levels and adipocyte density in rats (Lejonklou et al., 2017). This evidence concerns the gene INS and Insulin resistance.