INS and Hepatic fibrosis: ITGA7, important for insulin and glucose metabolism, Taylor (2018) showed hypermethylation, as did PLXND1, a therapeutic target in liver fibrosis and associated with adipocyte lipolysis (Strawbridge et al., 2016; Yagai et al., 2014), further linking these epigenetic changes to the metabolic disruptions observed due to prenatal-BPA treatment (Veiga-Lopez et al., 2016).