NDUFS8 and non-small cell lung carcinoma: In the context of cancer, Hsiao et al. reported that high NDUFS8 expression is associated with poorer overall survival in non-small cell lung cancer (NSCLC) [18], while Jiang et al. demonstrated that exogenous overexpression of NDUFS8 enhances complex I activity and contributes to radioresistance in NSCLC cells [19].