CD8A and neoplasm: SUVmax T-Lesion/ SUVmean fat-tissue ratio on [99mTc]Tc-Tilmanocept SPECT/CT at 1-h was significantly associated with tumour response at three months (p = 0.005), total cells densities for macrophages and CD8 + cells on multispectral immunofluorescence staining and poorer outcomes during the follow-up (p = 0.026).