CD206-positive (CD206 +) macrophages promote tumour growth, angiogenesis, invasion and metastasis by suppressing anti-tumour immunity and enhancing tumour cell survival (12) through the production of IL10 and TGFbeta, two cytokines that inhibit the activation and function of T cells, NK cells and other immune cells (13). The gene discussed is TGFB1; the disease is neoplasm.