This reduces the clearance of translocated E. faecalis, worsening liver disease.[26] Additionally, studies indicate that KCs undergo necroptosis after severe Listeria infection, while MoMFs enhance antibacterial immunity through IFN‐γ‐mediated responses.[27] Using a wild‐type mouse model (Figure 5), we investigated how S. saprophyticus and T‐2 toxin dynamically disrupt hepatic macrophage homeostasis and contribute to liver disease progression. This evidence concerns the gene IFNG and listeriosis.