LAMA1 and neoplasm: Interestingly, we observed a reduction in LAMA1 (which is an important component of the basement membrane in healthy lungs)[45, 46] at tumor cell loci (Figure 6I,J right), suggesting that the tumor cells within the dECM‐tumors exert a synergistic influence to remodel their extracellular environment through combined ECM‐digestive and synthetic activities.