However, regulating the expression of METTL3 in a myocardial fibrosis model after MI or hypoxia intervention in CFs can affect the expression level of SMOC2 (Figure 5C,D); therefore, we initially believe that METTL3 can affect the proliferation and differentiation of CFs by regulating the expression level of SMOC2. Here, SMOC2 is linked to Myocardial fibrosis.