Our study also observed dynamic changes in METTL3 and ALKBH5 expression during myocardial fibrosis post‐myocardial infarction and in the proliferation and differentiation of hypoxic‐induced cardiac fibroblasts, suggesting that a compensatory mechanism involving METTL3 and ALKBH5 may also exist in the proliferation and differentiation of cardiac fibroblasts, albeit this hypothesis warrants further experimental validation in the future. This evidence concerns the gene METTL3 and myocardial infarction.