Notably, while paxillin protein levels were seemingly unaltered in heart disease (40), genome-wide association studies nevertheless indicate links with “left ventricle wall thickness,” “left ventricular function,” “hypertrophic cardiomyopathy,” and other traits related to heart disease [National Human Genome Research Institute–European Bioinformatics Institute genome-wide association study (NHGRI-EBI GWAS) Catalog (67)]. This evidence concerns the gene PXN and hypertrophic cardiomyopathy.