PLAT and coronary artery disorder: To benchmark efficacy using spirometry and oxygen saturation, children with Fontan-palliated CHD without a history of PB, with and without protein losing enteropathy (PLE), and healthy children were enrolled in a control arm that did not receive tPA.<h4>Results</h4>Of the 10 patients with PB screened for enrollment, eight qualified for immediate treatment with inhaled tPA.