In particular, research showed that gut bacterial caseinolytic protease B (ClpB), produced by several intestinal microorganisms, is implicated in the production of autoantibodies cross-reactive with α-melanocyte-stimulating hormone (α-MSH), which are associated with altered feeding and emotional behaviors in patients with EDs, in particular those with BN and BED (Tennoune et al., 2014). Here, CLPB is linked to Ehlers-Danlos syndrome.