LGALS8 and gastroenteritis: In the case of Salmonella, a Gram-negative bacterium associated with food poisoning and gastroenteritis, rupture of the PcV induces the recruitment of LGALS3 (galectin 3) LGALS8 and LGALS9, with LGALS8 playing a unique role as a danger receptor that inhibits bacterial proliferation (Figure 1A) [26].