While the risk for hospitalization is low with Omicron (89), our data from hospitalized patients with high Omicron viral loads (41, 42, 47, 49) or pneumonia (43) show that patients may benefit if (isotonic) SNI and saline gargling are started early; this is associated with increases in lymphocytes and a reduction in CRP (41, 46, 49, 68). The gene discussed is CRP; the disease is pneumonia.