FAN administration alleviated the inhibition of the Nrf2 pathway in the liver specimens of rodents with hepatic fibrosis by increasing the Nrf2 expression and its downstream detoxification enzymes’ (HO-1, SOD1, and CAT) protein levels and decreasing the protein level of Keap1 (Figures 5B–G). Here, HMOX1 is linked to Hepatic fibrosis.