To further identify the relevance of these 42 proteins withautism-related synaptic and behavioral deficits, we searched the SFARI Gene database.Searching results revealed that mutations of 7 among these 42 genes (Dlg4, Eif4g1,G3bp2, Ntrk2, Rap1gap, Psmd6 and Cpeb4, as shown in Fig. 4F) are associated with autism cases andDlg4 (encoding PSD-95 protein) and Eif4g1 (encodingeIF4G1 protein) are reported with the highest numbers of autism cases (Fig. 4F). This evidence concerns the gene RAP1GAP and autism.