LERFS and colorectal carcinoma: Although the relative abundance of these B cell subtypes showed no significant differences across groups, we observed differential transcriptional patterns such as plasma cell-specific upregulation of long noncoding RNAs (lncRNAs) (LINC00355, AC004556.3, AC105402.3, and LERFS) in LS-CRC and SFRP1 (Secreted Frizzled-Related Protein 1) in LS (Figure 3B; Table S4).