IL4 and influenza: For example, using all the combined genes found in human subjects of all sexes stimulated by all or individual influenza vaccines, we found many shared statistically significantly differential innate, adaptive, and cytokine signaling immune pathways, such as interleukin-10 signaling (False Discovery Rate (FDR) adjusted (the same below) p-value = 1E-5), ‘interleukin-4 and interleukin-13 signaling’ (p-value = 3.37E-7), and neutrophil degranulation (p-value = 1.1E-2).