F2 and laryngotracheoesophageal cleft: In addition, coagulation abnormalities such as prolonged prothrombin time (PT), international normalized ratio (INR), and thrombin time (TT) were also significantly elevated in HBV-LC patients, which might attribute to insufficient hepatic synthesis of coagulation factors (Aiza-Haddad et al., 2024; Lisman et al., 2021)