RT‐qPCR and Western blot analyses showed that miR‐217 and TSHZ2 expressions were significantly increased in the tumor tissues of the Lv‐miR‐217 + oe‐NC group compared to the Lv‐NC + oe‐NC group, whereas DNMT1, SHH, and GLI1 expression were significantly decreased. Here, TSHZ2 is linked to neoplasm.