Further studies demonstrated that infection of antrum-derived gastric organoid cells with H. pylori led to an increase in the expression of the stem cell marker leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5), suggesting that H. pylori infection may influence stem cell dynamics, potentially contributing to epithelial repair processes or, conversely, to pathological conditions such as cancer initiation (Nascakova et al., 2024). The gene discussed is LGR5; the disease is infection.