TGFB1 and neoplasm: They exposed human neutrophils to either a TAN1 cocktail (containing LPS, IFN-β, and IFN-γ) or a TAN2 cocktail (containing L-lactate, adenosine, TGF-β, IL-10, PGE2, and G-CSF) and demonstrated that each respective cocktail could polarize mature neutrophils into tumor-associated subsets (159).