CD4 and neoplasm: Following standard quality control, normalization, and dimensionality reduction procedures, UMAP visualization revealed distinct clustering of major cell populations, including CD4+ T cells, tumor epithelial cells, CD8+ T cells, inflammatory monocytes, tumor-associated macrophages (TAMs), NK cells, endothelial cells, cycling CD8+ T cells, proximal tubular epithelial cells, mural cells, mast cells, B cells, plasma cells, and plasmacytoid dendritic cells (pDCs) (Figure 10A).