Bulk RNA sequencing data showed that the mRNA expression of Panx1 was significantly upregulated in the vast majority tumors in the Oncomine database, including breast cancer, cervical cancer, colorectal cancer, esophageal cancer, gastric cancer, head and neck cancer, kidney cancer, lymphoma, leukemia, lung cancer, pancreatic cancer, and sarcoma. This evidence concerns the gene PANX1 and colorectal cancer.