USP36 promotes the progression of esophageal squamous cell carcinoma (ESCC) through the Hippo/YAP axis; USP36 enhances the invasiveness of glioblastoma by stabilizing SNAIL2, and USP36 accelerates the progression of hepatocellular carcinoma (HCC) through synergistic action with TP53 (Sun, 2022; Li, 2023; Chang, 2023). The gene discussed is USP36; the disease is esophageal squamous cell carcinoma.