The enhanced tumor-suppressive efficacy of C/M@Alb NCs was confirmed by H&E, Ki67, and TUNEL staining of the E0771 primary tumor section, which revealed that C/M@Alb NCs caused severe damages to tumor cell with stronger apoptosis (Fig. S21), confirming the cooperative potent antitumor efficiency of C/M@Alb NCs against primary E0771 breast tumors and lung metastasis inhibition. This evidence concerns the gene ALB and breast neoplasm.