Expression validation in the transcriptome, TCGA–BLCA, and GSE13507 datasets confirmed the up-regulation of APOL1, DHX34, and TNK2, and the down-regulation of AHNAK, CSPG4, NCAM1, and PCDHB4 in the cancer group (Figure 3d). The gene discussed is APOL1; the disease is bladder transitional cell carcinoma.