ACTA1 and non-small cell lung carcinoma: Regarding their major subtypes, LRRC15+ myCAFs are dominant in NSCLC [22, 44, 79] (Fig. 2F); yet there is evidence that α‐SMA+ myCAFs abundance and expression of fibrillar collagens and other fibrosis markers are higher in LUAD than LUSC, particularly in smokers [54, 79].