POMC and pituitary gland adenoma: Sixty-five (95.6%) patients underwent trans-sphenoidal surgery (TSS), 44 of them (67.7%) had a resected adenoma expressing ACTH and/or T-PIT, 7 (10.8%) had no pituitary adenoma in pathology, and for 14 (21.5%) patients we did not have available pathology reports.