Furthermore, we found an upregulation of expression of autoimmunity associated genes in patients with RA, such as BM1 that is expressed in antibody secreting cells, interleukin enhancer-binding factor 3 (ILF3), a known autoantigen that is only seen in patients with RA and TCF1 (encoded by TCF7) a transcription factor known to contribute to the perpetuation of the autoimmune response. The gene discussed is TCF7; the disease is rheumatoid arthritis.