Additionally, Mknk1 is involved in regulating inflammatory responses (Joshi and Platanias, 2012) and is differentially expressed in the periphery (e.g., blood, dorsal root ganglia) in breast cancer survivors and mice with paclitaxel-induced peripheral neuropathy compared with controls (Kober et al., 2020). Here, MKNK1 is linked to peripheral neuropathy.