We found that patients with non–small cell lung carcinoma (NSCLC, n = 489), CRC (n = 228), and esophagogastric carcinoma (EGC, n = 111) had better OS with high compared with low intratumoral CD8+, PD-1+, and/or CD8+PD-1+ cells (log-rank P ≤ .05, Figs 2B-2D). This evidence concerns the gene CD8A and non-small cell lung carcinoma.