VEGFA and melanoma: These unpolarized or M1- or M2-polarized BMDMs were then co-cultured with syngeneic D5 mouse melanoma cells transduced to overexpress HER2 (termed D5-HER2 cells) for further characterization of co-phagocytosis of a recombinant VEGFA (labeled with pH-sensitive pHrodo green) after overnight treatment in the presence of control mouse IgG, a combination of anti-VEGFA (G6.31.2a) and anti-HER2 (4D5.2a) antibodies, or TG-VHS.