TG and herpes simplex infectious disease: However, in the low-salinity plus taurine group, the upregulated genes compared to the C group were mainly enriched in cholesterol metabolism, lysosomes, antigen processing and presentation, herpes simplex virus 1 (HSV-1) infection and legionellosis when compared with the saline water group, while the downregulated genes were enriched in adrenergic signaling in cardiomyocytes, thyroid hormone synthesis, legionellosis and animal autophagy.