It was shown that the overexpression of LOXL1 can induce epithelial–mesenchymal transition (ETM) in gastric cancer cells, thus causing cell migration and metastasis, and is associated with tumor cells with a poorly differentiated histological type and with PD in gastric cancer, suggesting LOXL1 as a biomarker and a potential therapeutic target in gastric cancer. The gene discussed is LOXL1; the disease is gastric cancer.