TLR3 and viral infectious disease: In the present study, at the peak of infection (72 h), specific viral receptors, such as a receptor for dsRNA, encoded by the TLR3 gene, generated during most viral infections [59], was found to be positively expressed in the gills and spleen, enriching pathways such as the “immune response”, “biological process involved in interspecies interaction between organisms” and “response to another organism”.